??涓???浜т腑???哄???硅??/h3>
?ㄥ??涓???浜т腑锛??哄????????搴??ㄥ凡缁?寮?濮??剧?板?哄法澶х??娼???????杩?绮剧‘???哄??缂?杈?锛?绉?瀛﹀?浠??藉??硅????????????绉?锛???楂??剁??浜ф?ц?藉?????????с??渚?濡?锛???杩??哄???硅???绉?瀛﹀?浠??藉??硅?插?烘?村??楂???????????绉?锛???灏??剧????????锛???楂?浜ч????
?ㄧ??????ュ?哄???硅???归???绉?瀛﹀?浠???ㄧ??绌跺?浣???杩??哄??缂?杈???楂??????ュ悍姘村钩??瀵垮?姐??渚?濡?锛???杩?淇??圭?????哄??锛?绉?瀛﹀?浠??藉???灏???浜???浼??х?剧????????锛?浣跨??????娲昏川??寰??版??楂???
琛?涓轰?璁??
????DNA??绌惰?涓虹??瑙ｇ????琛?涓哄??璁????渚?浜???瑕???绉?瀛﹀?虹?????杩??????????哄??缁?锛?绉?瀛﹀??藉???ず?哄????哄??涓?????琛?涓虹?瑰?锛?濡?蹇?璇?搴︺????浠??у??绀句氦琛?涓虹?稿?炽??杩?涓?浠????╀??村ソ?拌?缁????ч【??锛?杩?涓轰汉绫???浜??ㄧ??绌舵??渚?浜??扮??瑙?瑙???
浜虹被??????????DNA??绌朵?浠???ず浜????界??濂ョ?锛?杩?涓烘???ュ?诲?????涓?甯︷????ヤ??????????芥?с????杩?娣卞?ヤ?瑙ｈ?浜??ㄧ?╃???哄??缁?锛???浠??藉?寮????烘?寸簿?????存??????娌荤???规?锛?瑙ｅ?冲?ㄥ?绉绘????鹃?锛?骞舵?村ソ?扮??瑙ｅ???ч【??浠???瀹??┿??杩?浜???绌舵????涓?????涓虹?瀛﹁?姝ュ???轰?璐＄???涔?涓轰汉绫诲?ュ悍??绂?绁?甯︽?ヤ?宸ㄥぇ??甯?????
???哄??缁?涓?浜虹被?ュ悍
?????哄??缁???绌跺?ㄥ?绉??归?㈠?浜虹被?ュ悍????瑕???涔????????绉?浜虹被?剧?????????舵ā??锛?濡???????蹇???????绁?缁???琛??х?剧????????杩???绌剁????DNA锛?绉?瀛﹀??藉??村ソ?扮??瑙ｈ?浜??剧??????ョ?????哄?讹?骞跺????扮??娌荤???规????????哄??缁???绌惰?涓哄???版?扮????ユ不???剁?瑰?????╂??渚?浜?瀹?璐电???版????
?㈢???浜?r??r????DNA??锛???ず???藉ゥ绉???绉?瀛︿???
?ㄤ?涓??ㄥ??锛???浠?凡缁?浜?瑙ｄ?浜虹被??????????DNA?ㄨ???????涓????诲???绌朵腑????瑕?浣??ㄣ?????ㄥ??灏?杩?涓?姝ユ繁?ユ?㈣?杩?浜??哄??缁??ㄥ?ュ悍?????ュ?诲?涓???搴??ㄥ?????灞?绀哄?浠??浣?涓烘??浠??????ュ甫?ユ?扮????ュ????????芥?с??
?㈢?浜虹??DNA
浜虹??DNA???瀛︾??绌剁???稿?涔?涓?锛?瀹????????浠?????????浼?淇℃??????杩?瀵逛汉绫诲?哄??缁?????ュ?ㄩ?㈣В??锛?绉?瀛﹀?浠????帮?浜虹被?哄??缁??????绾?0,000??5,000涓??哄????杩?浜??哄???冲?浜???浠???澶?璨???琛?涓恒???ュ悍?跺?碉????虫????浠????烘?т?????????
浜虹被?哄??????绌朵?浠?甯??╂??浠???瑙ｈ??韩??璧锋?锛?杩?涓哄?诲?????涓??????╂?????棰???甯︽?ヤ?宸ㄥぇ??绐??淬??渚?濡?锛???杩??哄??缂?杈?????RISPR锛?绉?瀛﹀?浠???互绮剧‘?颁慨?逛汉??DNA锛?浠???娌荤????浼??х?剧????浜虹被?哄??缁?????绌惰?涓烘??浠??瑙ｄ汉绫昏?????绋???渚?浜???瑕?渚??????ず浜?浜虹被濡?浣?浠??ょ?挎??????ワ?骞跺?ㄦ极?跨??杩???杩?绋?涓???娓?褰㈡??浜??颁唬浜虹被??
????DNA锛?涓?涓?法?╃???妗ユ?
????DNA??绌跺?ㄨ法?╃??哄????绌朵腑??????瑕?浣?缃??????浜虹被?ㄥ?哄??缁?涓???璁稿??镐技涔?澶?锛?杩?浣垮?????涓轰??诲???绌朵腑?????虫ā????渚?濡?锛??????ㄥ??ㄧ????????戒?涓?浜虹被??甯哥?镐技锛?杩?浣垮?????涓哄?ㄥ?绉绘???绌剁????瑕?瀵硅薄??
??杩?瀵圭???????NA杩?琛??ㄩ?㈣В??锛?绉?瀛﹀?浠????帮??????哄??缁??????澶ю??哥害20,000涓??哄??锛??朵腑璁稿?涓?浜虹被?哄??楂?搴︾?镐技??杩?绉??哄???镐技?т负???ㄥ?诲???绌朵腑??搴??ㄦ??渚?浜????姐??渚?濡?锛????????ㄥ?楠?涓???互?ㄤ???绌朵汉绫昏?????剧??锛?浠???????ㄥ?ㄨ????绉绘?????????灞??????ㄥ??涓?棰?????搴??ㄤ?骞挎?锛???杩??哄??缂?杈???????互?硅?插?烘?撮?浜с???村?ュ悍?????浠???婊¤冻浜虹被瀵硅??绫荤????姹???
?哄??缂?杈??????ㄥ?ㄧ?╃??绌朵腑??搴???/h3>
?哄??缂?杈??????濡?CRISPR-Cas9锛?涓哄?ㄧ?╃??绌舵??渚?浜??????????????芥?с????杩??哄??缂?杈??????绉?瀛﹀?浠??藉?淇???ㄧ?╀腑????浼??剧??锛???楂?瀹?浠?????娲昏川????渚?濡?锛???杩??哄??缂?杈??????绉?瀛﹀?浠??藉?淇????涓?????浼??剧??锛?浣垮?浠????????﹀???剧?????版?般???哄??缂?杈??????ㄥ??涓???浜т腑涔??锋????瑕?搴??ㄣ??
渚?濡?锛???杩??哄??缂?杈??????绉?瀛﹀?浠??藉??归?????浣垮?浠??锋???撮?????浜ф???????村ソ???ュ悍?跺?点??
?ㄨ?娈佃法瓒??╃????㈢储涔???涓????浠????颁?浜虹被????????涔??寸??娣卞?昏??绯汇??杩?浜??ㄧ?╃??DNA??绌朵?浠??ㄥ?ㄤ?绉?瀛︾??杩?姝ワ?杩?涓烘??浠???瑙ｇ???界????川??渚?浜?瀹?璐电??瑙?瑙ｃ????杩?娣卞?ユ?㈢储杩?浜??ㄧ?╃???哄??锛???浠??浠??芥?村ソ?颁??ゅ??娌荤??瀹?浠??杩??藉????烘?存???????荤??????涓???????
杩??鸿法瓒??╃????㈢储涔???锛?璁╂??浠??村??娣卞?诲?拌?璇??扮???界??濂?濡???澶??锋?с??